Quotation Request Form
 
  • Your quotation Number is:  2047680
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  • We do not accept liability if for any reason the information you send us is, or proves to be, inaccurate for any reason.

  

     
      Now complete the form below, checking your input carefully.
 

  

 
 

Target protein details:

 

 

 

Protein sequence:
 (Required format)

Paste sequence(s) here in one of the supported formats.
 

Protein name and optional extra info:
(More information)

 e.g. sequence ID, regions of interest, any special requirements.
 
 

Protein solved 3-D structure:
(if available)
Low resolution and modelled structures are also acceptable.

     Either

 

 PDB Number:
(More info)

 

        Or

 Atomic coordinates:
(PDB file format)

Click here
for 3-D structure data input form
 
Due to their large size, we use this additional form to transmit your atomic coordinate data to a secure area of our server.
   
   
 

  Services required:

Consensus epitope prediction
(B cell) and annotation of
target protein.
  • Antigenicity (3 algorithms).
  • Flexibility (1 algorithm).
  • Hydrophilicity (2 algorithms).
  • Hydrophobicity (5 algorithms).
  • 2° structure prediction (2 algorithms).
  • PROSITE pattern motif searching.
  • Further relevant protein analysis.
  • Rank of epitopes as likely antigens.
 

Further analysis and annotation
of 4 strongest predicted
epitopes.
  • BLASTP database searching
    (optimised for epitope queries).
  • Protease cut-site mapping
    (for downstream epitope mapping/protein
     digestion, sequencing, MS analysis).
 

Analysis and epitope mapping
to target protein solved or modelled 3-D structure (if available).
NB Choose this option ONLY if protein PDB No. or atomic coordinates have been input above.
  • Degree of epitope residue surface exposure.
  • Epitope association with beta-turn structures.
  • Conformational epitopes.
  • Rank of epitopes as likely antigens.

 
 

 

 
 

  Analysis always includes:
 

 

  Identification of amino acid sequence pattern motifs (PROSITE).
 
 

 

  Reviewing available published literature and specialist protein databases
   for further information relating to your target protein and predicted epitopes.
 
 

 

  Beta-turn secondary structure analysis.
 
 

 

  Comment on N- and C-terminus regions.
 
 

 

  The effect of varying algorithm window size (where applicable).
 
 

 

  Transmembrane spanning regions.
 
 

 

  Signal/cell sorting sequences.
 
 

 

  PEST sequence analysis.
 
 

 

  Target protein physicochemical properties.
 
 

 

  Recommendations for epitope peptide synthesis and conjugation to carrier protein.
 
 

 

 


  Report is:   


About 50 pages in length and similar
in format to a published scientific paper,
your epitope prediction report is a detailed
document containing high quality graphics
and nice-view annotation of output data.		  

      A report is always sent as part of a service. An e-Report is sent unless
      you request otherwise below.
 
 

I request no e-Report
(This option requires that you request a hardcopy report)

Optional hardcopy report
(please select one of the following options)
  Either No hardcopy report        

Or               One hardcopy report with courier delivery to:
                                                 (no postal service)

  USA/non-UK Europe:    
  UK:  

 

      
      Rest of World:

 

      

 

    
 

Your details:

(*= required field)
*Your name:
Title:
*Company/Institution name:
*Company/Institution address:
*Postal/ZIP code:
*Your location:

 
Phone:

extn:
(please incl. country and area codes)
Fax:

 
*Your e-mail address:

 

 
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It is essential that this address is correct for your quotation request to be processed).
  *Our Response:
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(if any)		 (e.g. please mail hardcopy quotation as well)
 		  
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