We provide specialist bioinformatics services for epitope discovery and modification. A particular focus is epitope prediction for the identification and targeting of antibody epitopes.

Our specialist expertise and experience, spanning several decades.

An epitope discovery platform utilising consensus epitope prediction (and related protein modelling and annotation), and further epitope contextual analysis that incorporates protein structure, function and conservation.

Flexible services, which can be tailored to incorporate:

Significant savings of your time.

Quick, easy-to-use Internet-based service provision.

Competitive pricing structure.

Respect of your privacy and confidentiality of your information.

Links lists were recently updated, and expired and dead links removed.

Further revision, including the addition of many new links, is in progress.


ePitope Informatics listed in Nature feature articles:

 Click here for references.
 

Commercial services
 

	Prediction and contextual analysis of antibody epitopes. Relevant in silico analysis and annotation of target protein(s), epitope mapping to protein 3-D structure from prediction of both linear and discontinuous epitopes.
	A detailed service e-Report (using secure e-document delivery) incorporating publication quality graphics and high quality annotation of output data.
	A hardcopy report option.
	Online quotation request, ordering, enquiry, support and feedback facilities.
	Choice of secure and standard server facilities.
	No site registration.
	Holding none of your information on our servers or databases.

We offer a no obligation online quotation request form that allows you to select epitope prediction and analysis and target protein annotation service options. More easily, you can tailor our service to suit your needs.

Our molecular modelling platform includes use of high performance graphics workstations and stereoscopic 3-D viewing hardware (from NVIDIA and StereoGraphics/RealD), and a variety of software that includes Discovery Studio from Accelrys.

This platform allows our introduction of enhanced molecular analysis and modelling services for antibody epitope prediction and mapping to protein 3-D structure, which includes identification and contextual characterisation of both linear and discontinuous ("conformational") epitopes, and protein comparative modelling services.

Our epitope prediction and analysis services are offered with a competitive pricing structure, and our Internet-based utilities for secure service delivery are provided free of charge.
 

Updated links to relevant resources, literature references, and informational content related to protein analysis, annotation and antibody epitope prediction.

Currently, we do not provide services for T cell epitope prediction, but we provide links to online and other software resources.

  INFLUENZA EPITOPE RESOURCES

• Avian Influenza portal, plus link to PDF information (Aug. 2012) regarding outbreak of highly pathogenic H7N3 in poultry (FAO).

• Emerging Avian Influenza A (H7N9) Virus. Information about current outbreak in China from CDC Seasonal Influenza resource.

• GISAID - Global Initiative on Sharing Avian Influenza Data.

• H1N1 Flu Resource Centre The Lancet (from Elsevier).

• Influenza Research Database (IRD). Influenza and epitopes database and tools (BioDefence and Public Health Database); National Institute of Allergy and Infectious Diseases
  (NIAID/NIH). SARS and other coronavirus information available at this site.

• Influenza Virus Resource: Information, Search and Analysis
  at National Center for Biotechnology Information (NCBI).

• Pathogen Portal to the Bioinformatics Resource Centers (BRCs)
  (NIAID/NIH).

• Sporadic swine flu H3N2. Information from CDC Seasonal Influenza resource.

• Swine Flu Epitopes Analysis The Immune Epitope Database and Analysis Resource (IEDB/ NIAID/NIH).
   

 HUMAN PROTEIN ATLAS

 The Human Protein Atlas is an open, freely accessible resource for
 systematic exploration of the human proteome characterised by
 antibody proteomics (courtesy of The Swedish Human Proteome
 Resource (HPR) program, and part of the HUPO Human Antibody
 Initiative (HAI)). Antibodies are used for protein profiling,
 and the Human Protein Atlas shows expression and localization of
 proteins in a wide variety of normal human tissues and cancer cells.

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